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HIV transmission prevention drug atazanvir proved to be harmful for children

New research showed that a particular drug which blockages HIV transmission from mother to child also poses a remarkable threat on the future physical development of the child .This study was conducted by the research team of Harvard University. The study team found that the drug contributes in altering the regular development of the child. Even if the child is not born with the disease, he/she suffers many levels of physical and cognitive challenges in their later life.

The drug is called atazanvir. This drug is a part of a package that is used to prevent HIV transmission. This drug is also used in order to reduce chances of HIV transmission. Earlier study in this regard showed a probable threat that comes with the drag but wasn’t certain about it. Previous study revealed the chances of possible threat is extremely low. However, that study didn’t suggested people to change their treatment because of the threat,

The new study on HIV prevention drug was announced in the journal AIDS. The study team went through an intense research session. The team appointed 167 women to study the effects of the drug. These women received the drug atazanvir during pregnancy.  The team also studied cases of 750 patients who didn’t receive atazanavir drug. These patients were looked up thoroughly until their child became 1 year old.

 According to the study, children whose mothers were injected with the HIV prevention drug, suffered to a great deal of physical and cognitive challenge in their later life. Those children performed poorly in their language learning and social emotional development .There were also different level of change in the child’s behavior based on the time on when their mothers were injected with the drug. Social emotional score was hugely compromised in children whose mothers started the drug in the second or third trimester of their pregnancy .Language development in the children hampered regardless of the time of exposure of the drug. Cognitive, motor and adaptive performance based developments were also severely compromised. The study team explained that although small statistical distinction do not have huge clinical implications, however these implication deserves attention .According to the team “add another risk to the constellation of existing biological and socio-environmental risk factors to which these children are often exposed.”

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